Is long-term GLP-1 use considered safe, or is it meant to be short-term?

Current clinical guidance generally treats GLP-1 medication for chronic weight management as a long-term therapy, similar to how other chronic conditions are managed on an ongoing basis, rather than a short course meant to be stopped after a set period. That said, long-term safety data (beyond several years) is still accumulating as these medications are relatively newer for weight-management specifically, which is why ongoing monitoring remains part of long-term use. References: https://obesitycanada.ca/healthcare-professionals/adult-clinical-practice-guideline/