A second dose of a short-acting stimulant in the afternoon: does that actually explain nighttime sleep trouble?

It genuinely can, and this is one of the more common, somewhat under-discussed causes of nighttime sleep trouble for people using a second afternoon dose of a short-acting stimulant to cover evening symptoms. Even a modest afternoon dose can still be partially active into the evening depending on timing and individual metabolism, and because short-acting formulations are often perceived as clearing the system quickly, people sometimes don't connect a late afternoon dose to sleep trouble hours later the way they might more readily suspect a long-acting morning dose. If the change is persistent, distressing, or affecting daily functioning, contact your provider through the FasTreat portal rather than changing medication on your own. Related reading: https://www.fastreat.com/en/blogs/adhd-sleep-problems-insomnia-relief-tips References: https://www.caddra.ca/canadian-adhd-practice-guidelines/