Is GLP-1 medication considered safe for people with a personal or family history of certain thyroid conditions?

It depends on the specific thyroid condition. A personal or family history of medullary thyroid carcinoma (MTC) or MEN 2 syndrome is a formal contraindication, based on findings of thyroid C-cell tumors in rodent studies (with human relevance not established but treated with caution). Other, more common thyroid conditions (like general hypothyroidism) aren't automatic contraindications but should still be disclosed to your provider as part of a full history review. References: https://obesitycanada.ca/healthcare-professionals/adult-clinical-practice-guideline/