Does GLP-1 medication affect fertility or pregnancy planning at all?

GLP-1 medications are not recommended during pregnancy and are generally advised to be discontinued before actively trying to conceive, per product labeling guidance. Weight loss itself offers no benefit to a pregnant person and pregnancy-specific safety data for these drugs is limited. Separately, weight loss achieved through the medication (particularly in people with PCOS-related infertility) has been associated with improved ovulation and unexpected pregnancies in some cases, so fertility can be indirectly affected through the weight-loss pathway even though the drug itself isn't meant to be used once pregnant. References: https://obesitycanada.ca/healthcare-professionals/adult-clinical-practice-guideline/