What's the difference between liraglutide and semaglutide for weight management?

Both are GLP-1 medications, but liraglutide (brand name Saxenda for weight management) is an earlier-generation option that requires daily injections, while semaglutide (Wegovy) is dosed weekly. Clinical trials have generally shown semaglutide producing greater average weight loss than liraglutide, which is part of why it's become more commonly prescribed, though liraglutide is still a legitimate option for some patients. References: https://obesitycanada.ca/healthcare-professionals/adult-clinical-practice-guideline/