Who actually gets ADHD benefit from bupropion in Canada?

Bupropion, including Wellbutrin and related products, is not labelled for ADHD in Canada; it is indicated for depression and other labelled uses depending on the product. Some adults with ADHD may still be considered for it, but that is a third-line, off-label option in CADDRA guidelines, not a first-line ADHD medicine, and CADDRA advises consulting an ADHD specialist because the use is off-label. If the change is persistent, distressing, or affecting daily functioning, bring a brief timeline to the prescribing clinician rather than changing the dose independently. References: https://www.caddra.ca/wp-content/uploads/Canadian-ADHD-Practice-Guidelines-4.1-January-6-2021.pdf https://www.caddra.ca/wp-content/uploads/CADDRA_ADHD-Medication-Chart_May2026.pdf https://pmc.ncbi.nlm.nih.gov/articles/PMC6109107/